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Ck. 67 Syntetisk metodologi i total syntese ( efterår 2007 - 5 ECTS )

Rammer for udbud

  • Uddannelsessprog: (se under Undervisnings- og arbejdsform)
  • Niveau: Advanced.
  • Semester/kvarter: 1st and 2nd quarter.
  • Timer per uge:
  • Deltagerbegrænsning:
  • Undervisningssted: Århus
  • Hovedområde: Det Naturvidenskabelige Fakultet
  • Udbud ID: 7697

Formål

In this course we will examine contemporary synthetic methodology for the construction of complex molecules.

Indhold

The discussions in the course will include the types of synthetic approaches employed, including key chemical reactions and reagents used in the synthesis. Important organic transformations such as pericyclic, ionic and radical reactions will be covered, where emphasis will be made on the mechanisms, selectivity and stereochemistry.

Læringsmål

At the end of the course the student should be able to:

· analyse and discuss the retrosynthesis of complex organic compounds
· classify the important protecting groups in organic synthesis
· apply knowledge of organic reactions to the synthesis of complex organic compounds
· reflect over the structure of complex organic compounds
· describe the mechanism for important organic reactions used in modern organic synthesis

Faglige forudsætninger

Four years of study including the minor subject of chemistry.

Underviser

Troels Skrydstrup.

Undervisnings- og arbejdsform

4-6 hours of lectures per week. English.

Litteratur

Classics in Total Synthesis, K.C. Nicolaou and E.J. Sorensen, VCH Publishers, Weinheim, 1996.

Eksamensterminer

Exam: After 2nd quarter
Reexam: On agreement with teacher. 

Udbyder

Kemisk Institut.

Tilmelding til undervisning

Department of Chemistry.

Studieordning og bedømmelse

Kandidatuddannelsen i kemi

  • Mundtlig, bedømt efter 7-skala med intern censur

Kandidatuddannelsen i medicinalkemi

  • Mundtlig, bedømt efter 7-skala med intern censur


  • Take-home exam
  • Oral exam. 30 minuttes. No preparationtime. No materials permitted.
  • Mark is given based on the Danish grading scale (7-point scale) 
  • Internal examiner

Oral exam based of assigned syntheses.