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Syntetisk metodologi i total syntese ( efterår 2008 - 5 ECTS )

Rammer for udbud

  • Uddannelsessprog: engelsk
  • Niveau: Kandidatkursus.
  • Semester/kvarter: 2nd quarter.
  • Timer per uge: 4-6
  • Deltagerbegrænsning:
  • Undervisningssted: Århus
  • Hovedområde: Det Naturvidenskabelige Fakultet
  • Udbud ID: 7891

Formål

In this course we will examine contemporary synthetic methodology for the construction of complex molecules.

Indhold

The discussions in the course will include the types of synthetic approaches employed, including key chemical reactions and reagents used in the synthesis. Important organic transformations such as pericyclic, ionic and radical reactions will be covered, where emphasis will be made on the mechanisms, selectivity and stereochemistry.

Læringsmål

At the end of the course the student should be able to:

· analyse and discuss the retrosynthesis of complex organic compounds
· classify the important protecting groups in organic synthesis
· apply knowledge of organic reactions to the synthesis of complex organic compounds
· reflect over the structure of complex organic compounds
· describe the mechanism for important organic reactions used in modern organic synthesis

 

Faglige forudsætninger

Four years of study including the minor subject of chemistry.

Underviser

Troels Skrydstrup.

Undervisnings- og arbejdsform

4-6 hours of lectures per week.

English.

Litteratur

Classics in Total Synthesis, K.C. Nicolaou and E.J. Sorensen, VCH Publishers, Weinheim, 1996.

Eksamensterminer

Exam: After 2nd quarter
Reexam: On agreement with teacher.

Udbyder

Kemisk Institut.

Tilmelding til undervisning

Department of Chemistry.

Studieordning og bedømmelse


Kandidatuddannelsen i medicinalkemi

  • Mundtlig, bedømt efter 7-skala med intern censur


A mark is given in the Danish grading scale (the 7-point scale) based on 30 minutes oral exam of assigned syntheses.
No preparation time and no aid allowed.
Internal examiner (intern censor).